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KMID : 0361020150580040229
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Korean Journal of Otolaryngology - Head and Neck Surgery
2015 Volume.58 No. 4 p.229 ~ p.235
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Optical Imaging and Its Clinical Application in Otorhinolaryngology
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Lee Sang-Joon
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Abstract
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Optical imaging visualizes tissue function and structure by analyzing the properties of absorption, scattering, or reflection. Light in the near-infrared spectrum relatively penetrate human tissue well. Diffuse optical imaging (DOI) is a functional imaging modality which can evaluate the perfusion and metabolism of human tissue and tumor by analyzing the optical properties of hemoglobin, water, and lipid. Optical coherence tomography (OCT) acquires the cross-sectional images by analyzing the coherence pattern of the reflected light from the human tissue. OCT has higher resolution more than 15 times compared to conventional imaging modalities like ultrasonography, computed tomography, or magnetic resonance imaging. Optical imaging has advantages of harmlessness, noninvasiveness, and high resolution. However, it has limitation in the penetration depth. In this review, mechanism of DOI and OCT and their clinical application in the otorhinolaryngology field will be discussed.
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KEYWORD
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Diffuse optical imaging, Near-infrared, Optical coherence tomography
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